IndraLab

Statements

Zinc atom activates KCNMA1. 3 / 3
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"As for BK channel activation by Zn , voltage-sensor activation was not required and ΔV was diminished by lowering pH (Figure 3B, D)."
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"Extracellular Zn activates Slo1 BK channels when they are coexpressed with Zn-permeable TRPM7."
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"50 , 58 In fact, this Zn 2+ -binding site is conserved in Slo2.1 but not present in Slo1 or Slo3, suggesting that, by binding to distinct sites, Zn 2+ can elicit opposite effects on Slo2.2 and Slo1."
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