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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Ethanol activates HCN1. 2 / 2

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"The change in Ih in the HCN1 channel caused by ethanol withdrawal is mediated by increases in cAMP, which binds to a cyclic nucleotide binding domain (CNBD) on the COOH-terminus of the channel."

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"The ethanol withdrawal procedure significantly increased the numbers of HCN1 positive cells in the Hip (t = 5.225, P < 0.001; Figures XREF_FIG) and the NAc (t = 14.618, P < 0.001; Figures XREF_FIG)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...