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USP39 activates cell migration. 5 / 5
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"Third, we demonstrated that USP39 knockdown inhibits cell migration and invasion by upregulating p53 and the downstream proteins MMP2 and MMP9 [XREF_BIBR]."
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"In addition, we conducted transwell assays to detect cell movement and the results revealed that doxycycline-induced USP39 knockdown drastically suppressed A549 and H1299 cell migration (Fig. S2G, H)."
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"Third , we demonstrated that USP39 knockdown inhibits cell migration and invasion by upregulating p53 and the downstream proteins MMP2 and MMP9 [ 31 ] ."
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"Transwell assay also showed that the enhanced cell migration induced by USP39 overexpression was repressed by GLI1 knockdown (Fig. 6G, H)."
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"As shown in XREF_FIG A-F, USP39 knockdown reduced the cell migration and invasion of both USP39KD cells in comparison to the control cells (* p < 0.05, ** p < 0.01, **** p < 0.0001)."
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