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USP47 increases the amount of epithelial to mesenchymal transition. 2 / 2

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"In line with the in vitro findings, knockdown of USP47 abrogated the expression of EMT markers in transplanted tumors, and this led to suppression of progression and invasiveness of CRC cells."

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"After validating USP47 alterations using MRM and antibody based assays, we demonstrated that the chemical inhibition of USP47 with the inhibitor P5091 reduced expression of EMT markers and reverted morphological changes in MCF-10A cells undergoing EMT."

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IndraLab

Statements

USP47 increases the amount of epithelial to mesenchymal transition. 2 / 2

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