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EMMAA Bob with Bioagents

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

TP53 binds CDK5RAP3 and MDM2. 4 / 4

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"To confirm and further examine LZAP binding to HDM2 and p53, complex formation was investigated using recombinant proteins in cell-free system."

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"LZAP binds p53 and HDM2."

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"Taken together, our results propose that LZAP binds both HDM2 and p53, and regulates p53 levels in a HDM2-dependent manner."

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"These results suggested that LZAP and p53 independently bind different parts of HDM2."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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