IndraLab

Statements

BMP4 increases the amount of HCN4. 3 / 3
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"The present results indicated that Bmp4 promotes Hcn4 expression via upregulation of Gata4, while transcription of Shox2 and Tbx3 was not affected by Bmp4."
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"It has been indicated that exogenous Bmp4 promotes the mRNA and protein expression of Hcn4, suggesting that Bmp4 is a critical factor in the differentiation of Tbx18 + EPCs into pacemaker like cells."
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"In vitro Bmp4 promoted the expression of Hcn4 in Tbx18 + EPCs via lineage tracing of Tbx18 : Cre and Rosa26R EYFP mice, which was likely due to upregulation of Gata4 expression."
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