IndraLab

Statements

SLC6A1 activates KCNQ3. 5 / 5
| 5
sparser
"We recently discovered that the inhibitory neurotransmitter γ-aminobutyric acid (GABA) directly activates Kv channels KCNQ3 and KCNQ5."
31701029
sparser
"Here, phylogenetic analysis, electrostatic potential mapping, in silico docking, electrophysiology, and radioligand binding assays reveal that the anticonvulsant binding pocket evolved to accommodate endogenous neurotransmitters including γ-aminobutyric acid (GABA), which directly activates KCNQ5 and KCNQ3 via W265."
29748663
sparser
"Remarkably, Manville et al. have recently reported that the neurotransmitter γ-aminobutyric acid (GABA) and various metabolites (β-hydroxybutyric acid and γ-aminoβ-hydroxybutyric acid) directly activate Kv7.3 and Kv7.5 but not Kv7.1, 2, and 4 ."
32676036
sparser
"We recently discovered that the inhibitory neurotransmitter γ-aminobutyric acid (GABA) directly activates Kv channels KCNQ3 and KCNQ5."
31925247
sparser
"Remarkably, Manville et al. have recently reported that the neurotransmitter γ-aminobutyric acid (GABA) and various metabolites (β-hydroxybutyric acid and γ-amino-β-hydroxybutyric acid) directly activate Kv7.3 and Kv7.5 but not Kv7.1, 2, and 4 ( xref )."
32676036