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Canrenoic acid inhibits KCNH2. 2 / 2

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"Very recently, it was demonstrated that spironolactone and its main metabolite, canrenoic acid (CA), inhibited Kv11.1 [human ether-a-go-go (HERG)] channel currents recorded in stably transfected Chine[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Both spironolactone (SP) and its main metabolite, canrenoic acid (CA), prolong cardiac action potential duration and decrease the Kv11.1 (HERG) current."

15980874

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Canrenoic acid inhibits KCNH2. 2 / 2

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