IndraLab

Statements


CYLD inhibits SQSTM1. 2 / 2
| 2

reach
"As we described here for YOD1, CYLD is acting on TRAF6 and p62 complexes, but - in contrast to YOD1 - CYLD is not preventing the formation of TRAF6 and p62 aggregates, but is recruited to TRAF6 by p62."

reach
"We found that knocking down CYLD increase autophagosome-lysosome fusion restored autophagic flux to reduce the p62 accumulation in PA-stimulated NRCMs."