IndraLab

Statements

CYLD inhibits SQSTM1. 2 / 2

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reach

"Knockdown of CYLD activation of the Wnt/β-catenin pathway to restore the autophagic flux and reduce the accumulation of p62 in PA- stimulated NRCMs, while an inhibitor of the Wnt/β-catenin pathway reversed this effect."

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reach

"As we described here for YOD1, CYLD is acting on TRAF6 and p62 complexes, but - in contrast to YOD1 - CYLD is not preventing the formation of TRAF6 and p62 aggregates, but is recruited to TRAF6 by p62."

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IndraLab

Statements

CYLD inhibits SQSTM1. 2 / 2

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