IndraLab

Statements


NMDAR activates CACNA1A. 2 / 2
| 2

sparser
"Because of the presence of NMDARs at many glutamatergic synapses, most studies find that NMDARs activate other voltage-dependent channels by boosting local synaptic depolarization (Schiller et al., xref ; Losonczy and Magee, xref ; Nevian et al., xref ; Makara et al., xref ; Branco and Häusser, xref ; Katona et al., xref ; Krueppel et al., xref )."

sparser
"This shows that the outward rectification of α5-GABA A Rs provides inhibitory GABAergic conductance on demand, perfectly suited to counterbalance voltage-dependent NMDAR activation with minimally affecting small AMPAR-mediated PSPs."