IndraLab

Statements

USP18 inhibits CDKN1A. 3 / 3
| 3
reach
"P21 down-regulation by USP18 was associated with inactive form of SAMHD1, phosphorylated at T592."
30068654
reach
"USP18 (UBP43) Abrogates p21 Mediated Inhibition of HIV-1."
30068654
reach
"USP18 downregulates p21 by accumulating misfolded dominant negative p53, which inactivates wild-type p53 transactivation, leading to the upregulation of key enzymes involved in de novo dNTP biosynthesis pathways and inactivated SAMHD1."
38675828