IndraLab

Statements

KCNK2 binds PCS/WT. 3 / 3
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"We therefore tested the ability of the Gi coupled GABA B receptor (GABA B R) to regulate the light gated current of the TREK1 and PCS/WT heterodimer."
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"This inhibition of the photo gated current in the TREK1 and PCS/WT heterodimer was 53.6 +/- 8% (n = 8), similar to the 60.6 +/- 5% (n = 8) inhibition of total current in WT alone (p> 0.7, t-test)."
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"We next investigated the regulation of the TREK1 and PCS/WT heterodimer channel by internal modification induced by GPCR activation."
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