IndraLab

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USP18 leads to the dephosphorylation of RCAN1. 2 / 2

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"USP18 de-ubiquitinates TAK1, thereby blocking phosphorylation of RCAN1, an inhibitor of calcineurin."

26766444

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"Thus, USP18 and TRIM30alpha both inhibit RCAN1 phosphorylation and thereby inhibit NFAT activation.Usp18 upregulation in Rspo3- and Evi-iECKO lung EC was validated by RT-qPCR."

26766444

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IndraLab

Statements

USP18 leads to the dephosphorylation of RCAN1. 2 / 2

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