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USP40 activates CFLAR. 4 / 4
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"These findings demonstrate USP40 promotes the stability of CFLAR at the protein level."
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"Using a reverse experiment in A549 cell lines, we showed that USP40 overexpression slightly increased CFLAR protein when GMEB1 was knocked down (Fig. 5e)."
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"We found that GMEB1 promoted the stability of CFLAR by de-ubiquitinase USP40."
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"Consequently, USP40 augmented the stability of CFLAR via its de-ubiquitinase activity."
31046799