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Dofetilide inhibits KCNH2-F656V. 1 / 1

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"For example, Lees-Miller et al. reported the IC 50 for dofetilide block of hERG F656V to be ~ 120-fold that of WT XREF_BIBR, whilst Mitcheson et al. reported values of 650-fold and 94-fold WT respectively, for F656A and Y652A mutations XREF_BIBR."

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IndraLab

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Dofetilide inhibits KCNH2-F656V. 1 / 1

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