IndraLab

Statements

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"UCH-L1 promotes EMT but similarly, the target substrates have not yet been identified."
28279784
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"A specific small molecule inhibitor, LDN57444, targeting UCH-L1 significantly inhibited HIF-1 alpha activity in the presence of endogenous UCHL1 expression and suppressed EMT reducing the incidence of distant tumor metastases."
28214899
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"These results indicate that UCH-L3 inhibits EMT by repression of EMT promoting genes such as Snail, Slug, Twist, and MMPs in normal prostate cell lines.In our previous report, we found that UCH-L1 exp[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
25194810
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"UCH-L1 induced EMT to increase the invasion and metastasis of prostate cancer cells."
34745437
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"We have already shown that UCH-L1, a close relative of UCH-L3, induces EMT and promotes metastasis in prostate cancer cells [11]."
25194810