IndraLab

Statements


USP22 inhibits IKBKB. 2 / 2
| 2

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"Importantly, we observed that USP18 and USP22, but not USP14, may directly inhibit IKK-beta activation through an NLRC5 independent mechanism."

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"They show that three USPs -- USP14, USP18, and USP22 -- fulfilled these criteria, but focused on USP14, as USP18 and USP22 could also inhibit IKKbeta activation directly in the absence of NLRC5."