IndraLab

Statements

U0126 inhibits JUN. 9 / 10
| 9
reach
"MEK inhibitor U0126 inhibits viral gene expression [XREF_BIBR] as well as the activation of host c-Fos, c-Jun, c-Myc, and STAT1 molecules."
27854239
reach
"Immunoprecipitation assay showed that hyperosmolarity increased the association of nuclear Sp1 with c-Jun, which was inhibited by U0126 and SP600125."
23816505
reach
"The persistent stretch highly activated c-Jun and elevated miR-34c expression; however, only U0126 significantly abolished the stretch induced activation of c-Jun and increase of miR-34c."
28580775
reach
"EGF increased p-ERK1/2, c-Fos, c-Jun, and p-c-Jun levels, which were inhibited by U0126."
19937979
reach
"S1P stimulated AP-1 subunits (c-Jun and c-Fos mRNA) expression was attenuated by U0126 and wortmannin, suggesting that MEK and PI3K and ERK cascade linking to AP-1 was involved in EGFR expression."
17902169
reach
"As shown in Figure XREF_FIG, both DPI and U0126 reduced the nuclear accumulation of JunB, c-Jun, and HIF-1alpha, but not Stat1 (which is DUOX2 independent) or Sp1 (which is constitutively expressed)."
27637085
reach
"Both U0126 pretreatment and c-Jun knockdown resulted, as expected, in reduced c-Jun activation and binding."
27708396
reach
"The MAPK inhibitor U0126 blocked ERK1/2 activation and reduced SC proliferation and also the upregulation of c-Jun."
24877090
reach
"GDF-15 or U0126 prevented c-Jun activation."
12514175