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OTUB1 increases the amount of MAF. 2 / 2

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"XREF_FIG b, Otub1 markedly reduced c-Maf polyubiquitination level but it was reversed by AVT, suggesting AVT inhibited Otub1 activity thus increasing the polyubiquitination level of c-Maf."

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"As a result, inhibiting OTUB1 decreases c-Maf protein levels and causes cell apoptosis in multiple myeloma cells (Xu et al., 2021)."

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OTUB1 increases the amount of MAF. 2 / 2

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