IndraLab

Statements

KLF5 binds ATXN3L. 18 / 20
4 | 6 8
reach
"ATXN3L directly binds to KLF5, decreasing its ubiquitination and thus degradation."
26079537
sparser
"The ATXN3L protein interacted with the KLF5 protein and decreased the KLF5 polyubiquitination."
26079537
reach
"To examine whether ATXN3L physically interacts with KLF5, we transfected Myc-ATXN3L and KLF5-3xFlag into HEK293FT cells and immunoprecipitated KLF5-3xFlag."
26079537
reach
"Finally, to test whether ATXN3L directly interacts with KLF5, we expressed and purified recombinant proteins, including KLF5-6xHis from E.coli and GST-ATXN3L from both HEK293FT cells and E.coli."
26079537
reach
"ATXN3L interacts with KLF5."
26079537
sparser
"ATXN3L directly binds, deubiquitinates, and stabilizes KLF5."
27844253
biogrid
No evidence text available
26079537
biogrid
No evidence text available
26079537
biogrid
No evidence text available
26079537
biogrid
No evidence text available
26079537
sparser
"ATXN3L directly interacted with KLF5, thus, reducing KLF5’s ubiquitination and degradation ( xref )."
36159990
reach
"ATXN3L directly binds, deubiquitinates, and stabilizes KLF5."
27844253
sparser
"ATXN3L directly binds to KLF5, decreasing its ubiquitination and thus degradation."
26079537
sparser
"ATXN3L interacts with KLF5."
26079537
sparser
"Ge et al. have demonstrated that the deubiquitinase ATXN3L can bind to KLF5 to prevent its WWP1-mediated ubiquitination and degradation, which leads to breast cancer proliferation [ xref ]."
38129384
sparser
"To examine whether ATXN3L physically interacts with KLF5, we transfected Myc-ATXN3L and KLF5-3×Flag into HEK293FT cells and immunoprecipitated KLF5-3×Flag."
26079537
sparser
"Finally, to test whether ATXN3L directly interacts with KLF5, we expressed and purified recombinant proteins, including KLF5-6×His from E.coli and GST-ATXN3L from both HEK293FT cells and E.coli ."
26079537
reach
"Ge et al. have demonstrated that the deubiquitinase ATXN3L can bind to KLF5 to prevent its WWP1-mediated ubiquitination and degradation, which leads to breast cancer proliferation [125]."
38129384