IndraLab

Statements

BAP1 increases the amount of KLF5. 5 / 5
| 5
reach
"BAP1 knockdown decreased the endogenous protein levels of KLF5 and its downstream target gene FGF-BP XREF_BIBR (XREF_FIG)."
26419610
reach
"The KLF5 mRNA levels were not decreased by BAP1 knockdown in the MCF10A and HCC1806 cells (XREF_SUPPLEMENTARY)."
26419610
reach
"Our data suggest that BAP1 promotes cell proliferation and migration, and enhances the expression of KLF5 and its downstream genes, including CyclinD1 and FGF-BP1, in the esophageal carcinoma cell line ECA109."
33529461
reach
"Subsequent investigations showed that WWP1 overexpression in melanoma cells could mediate K48-linked ubiquitination of KLF5 and induce its proteasomal degradation, whereas BAP1 overexpression reverted this modification and increased KLF5 protein expression (Jia et al. 2021)."
36918822
reach
"In addition, expression of KLF5, CyclinD1, and FGF-BP1 was increased by BAP1 overexpression and decreased by BAP1 knockdown."
33529461