IndraLab

Statements


BAP1 increases the amount of KLF5. 4 / 4
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"BAP1 knockdown decreased the endogenous protein levels of KLF5 and its downstream target gene FGF-BP XREF_BIBR (XREF_FIG)."

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"The KLF5 mRNA levels were not decreased by BAP1 knockdown in the MCF10A and HCC1806 cells (XREF_SUPPLEMENTARY)."

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"Our data suggest that BAP1 promotes cell proliferation and migration, and enhances the expression of KLF5 and its downstream genes, including CyclinD1 and FGF-BP1, in the esophageal carcinoma cell line ECA109."

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"In addition, expression of KLF5, CyclinD1, and FGF-BP1 was increased by BAP1 overexpression and decreased by BAP1 knockdown."