IndraLab

Statements

PRPF8 activates U4/U6. 2 / 2

| 2

reach

"Following de-ubiquitination of Prp8, Brr2 is free to promote unwinding of U4/U6, resulting in activation of the spliceosome [48]."

| PMC

➶

reach

"Indeed a C-terminal fragment of Prp8 — encompassing the RNaseH-like and Jab/MPN1-like domains — strongly stimulates Brr2-dependent U4/U6 unwinding in vitro [ 44 ]."

20089394

INDRA sources:

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IndraLab

Statements

PRPF8 activates U4/U6. 2 / 2

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