IndraLab

Statements

Ischemia activates KCNK2. 4 / 4
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"TREK channels also seem to be modulated by ischemia."
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"This action is due to lipidic compounds such as polyunsaturated fatty acid [ xref ] or lysophospholipids [ xref ] which are produced during ischemia that activates TREK and TRAAK channels."
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"In addition, TREK-1 was found to be upregulated by ischemia in astrocytes to enhance glutamate clearance and block neuronal death [13]."
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"This action is due to lipidic compounds such as polyunsaturated fatty acid [39] or lysophospholipids [7] which are produced during ischemia that activates TREK and TRAAK channels."
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