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USP51 increases the amount of ZEB1. 2 / 2

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"It was found that USP51 and constitutively photomorphogenic 9 signalosome subunit 5 promote EMT by stabilizing the expression of ZEB1, leading to increased tumor invasion and metastasis [27]."

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"In addition, knockdown of USP51 in A549 and DDP cells significantly induced apoptosis, decreased ZEB1 expression and increased cleaved poly ADP-ribose polymerase 1 (PARP1) and cleaved caspase-3 levels."

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IndraLab

Statements

USP51 increases the amount of ZEB1. 2 / 2

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