IndraLab

Statements



reach
"Analyzing a large set of endogenous BRG1-dependent and -independent ISGs, it was found that the HDACIs TSA, valproic acid (VPA), and HC toxin globally blocked the induction of STAT1/STAT2 target genes[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"We demonstrated that TSA treatment abrogated NAA inhibitory action on LPS/INF-γ mediated upregulation of iNOS and STAT1 (Fig. 3F-G)."

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"OSM, an IL-6 family cytokine, signals through the STAT pathway; recent reports show that HDAC activity plays an essential role in at least STAT1 signalling, and that TSA can therefore abrogate STAT1 induced gene expression [XREF_BIBR, XREF_BIBR]."