IndraLab

Statements

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"Then, we transfected siClaudin1 or siNC to MHCC97H cells stably overexpressed USP40 (Fig. 6F), CCK-8 and colony formation showed that the impact of USP40 upregulation on promoting cell proliferation could be limited by Claudin1 suppression (Fig. 6G, H)."
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"Knockdown of USP40 inhibits HCC cell proliferation, migration and stemness."
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"Overall, USP40 knockdown inhibited HCC cell proliferation, migration and stemness."
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"Overexpression of USP40 promotes HCC cell proliferation, migration and stemness."
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"In general, our findings suggest that USP40 upregulation can enhance HCC cell proliferation, migration and stemness."
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"USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1."
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"USP40 knockdown inhibits HCC cell proliferation, migration and stemness, whereas USP40 overexpression shows the opposite impact."
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