IndraLab

Statements

eidos
"These results suggest that eIF3F modulates cell proliferation by repressing translation ."
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"The proliferation rates of shRNA lentivirus infected PCa cells indicated that eIF3f knockdown markedly decreased the proliferation of PCa cells (XREF_FIG)."
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"Furthermore, we found that ectopic expression of sheIF3f # 1 resistant wild-type eIF3f rescued the proliferation rate of eIF3f knockdown cells (XREF_FIG)."
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"These results indicated that eIF3f knockdown caused inhibition of PCa cell proliferation at least partially through the suppression of Akt phosphorylation."
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"EIF3f knockdown in A549 cells was shown to inhibit cell proliferation and induce apoptosis."
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"We confirmed that the loss of eIF3f reduced the proliferation of PCa cells, both in vitro and in vivo."
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"EIF3f induces apoptosis by inhibiting protein synthesis and proliferation in pancreatic cancer and melanoma cells, whereas eIF3f may act as a negative regulator of translational effects, and its low expression protects melanoma cells from apoptosis [67]."
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