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Silicon dioxide inhibits NFKBIA. 2 / 2

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"N-Acetylcysteine and diphenyleneiodonium, both of which inhibit the accumulation of intracellular ROS, each blocked silica induced degradation of IkappaB-alpha but had no effect on that of the Prx enzymes, suggesting that ROS do not contribute to Prx proteolysis."

10558905

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"LPS and silica both induce degradation of IkappaB-alpha, and MG132 prevents LPS induced, but not silica induced, IkappaB degradation and NF-kappaB activation [63]."

9920280

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Silicon dioxide inhibits NFKBIA. 2 / 2

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