IndraLab

Statements

USP8 deubiquitinates KDR. 3 / 3
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"We now provide evidence that USP8 de-ubiquitinates VEGFR2."
26459808
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"Conversely, the de-ubiquitinating enzyme, USP8, is shown to mediate de-ubiquitination of VEGFR2, regulating VEGFR2 trafficking, proteolysis, and signal transduction 39."
30120232
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"USP8 depleted endothelial cells displayed altered VEGFR2 ubiquitination and production of a unique VEGFR2 extracellular domain proteolytic fragment caused by VEGFR2 accumulation in the endosome-lysosome system."
26459808