IndraLab

Statements

CD274 inhibits USP8. 2 / 2
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"Furthermore, in vitro, the USP8 inhibitor-αPD-L1 combination therapy promoted activated T cell-mediated tumor cell killing significantly compared with the USP8 inhibitor treatment group or the αPD-L1 therapy group (Fig. S9h, i)."
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"Additionally, in vitro, the USP8 inhibitor-αPD-L1 combination therapy did not significantly improve the killing of tumor cells by activated T cells in Cd274 KO KPC cells compared to parental KPC cells (Fig. S14a, b)."
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