IndraLab

Statements

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"We found that overexpression of wild-type USP35 promoted GC cell invasion and migration in vitro and facilitated tumorigenesis and metastasis in vivo."
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"We performed rescue experiments to determine whether USP35 promotes GC cell invasion and migration via Snail1."
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"6 B-E, Snail1 knockdown abolished USP35 overexpression-induced GC cell invasion and migration."
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"Furthermore, USP35 promoted the invasion and migration of GC cells depending on its DUB activity."
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"USP35 promotes GC invasion and migration, at least partially by regulating Snail1."
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"Transwell and scratch wound healing assays suggested that USP35 knockdown inhibited the invasion and migration of GC cells (Figs."
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"Knockdown of USP35 causes reduced proliferation, cell cycle arrest, increased apoptosis, and mitigated migration and invasion of HCC cells."
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"Moreover, USP35 knockdown impaired the migration and invasion capabilities of HCC cells (Fig. 3L–O)."
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