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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

CYLD decreases the amount of CDH2. 2 / 2

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"But in these cells, CYLD also inhibited the expression of N-cadherin, a protein known to promote tumor spread."

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"Snail1 dependent inhibition of CYLD transcription results in stimulation of Cyclin D1 and N-cadherin expression in melanoma cells, leading to enhanced proliferation, migration, and invasiveness of melanoma cells in vitro, as well as tumor growth and metastasis in vivo."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...