IndraLab

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Modified USP9X increases the amount of ITCH. 2 / 2

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"Overexpression of Usp9x increased 3D growth and invasion in PANC1 cells and up-regulated the expression of known Usp9x substrates Mcl-1 and ITCH."

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"We also show for the first time that Usp9x interacts with the Notch inhibitor Numb in NPs and loss of Usp9x significantly decreased Numb and Itch protein levels."

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INDRA sources:

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IndraLab

Statements

Modified USP9X increases the amount of ITCH. 2 / 2

INDRA sources:

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