IndraLab

Statements


IL1 activates TNFAIP3. 5 / 5
| 2 3

reach
"IL-8, TNFAIP3 and A20 and IL-6 (Early genes in response to TNF) were also rapidly induced by IL-1, peaking 1 h after stimulation."

reach
"It was shown that TNFAIP3 is induced by TNF and IL-1 and might therefore be involved in the regulation of NFkappaB dependent genes in diverse bacterial infections."

sparser
"The relatively small effect of the individual IKKα and IKKβ siRNAs on inhibiting IL-1-induced activation of A20 was seen in three separate experiments."

sparser
"Furthermore, TAK1 siRNA reduced IL-1-induced activation of the A20 gene to 3.2-fold ()."

sparser
"This result was also substantiated by studies of the role of IKKα and IKKβ on either IL-1 or TNFα activation of the A20 gene."