IndraLab

Statements

IL1 activates TNFAIP3. 6 / 6
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"This result was also substantiated by studies of the role of IKKα and IKKβ on either IL-1 or TNFα activation of the A20 gene."
12547194
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"Furthermore, TAK1 siRNA reduced IL-1-induced activation of the A20 gene to 3.2-fold ()."
12547194
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"The relatively small effect of the individual IKKα and IKKβ siRNAs on inhibiting IL-1-induced activation of A20 was seen in three separate experiments."
12547194
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"IL-8, TNFAIP3 and A20 and IL-6 (Early genes in response to TNF) were also rapidly induced by IL-1, peaking 1 h after stimulation."
16191192
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"IL-1 induced six of these genes (ATF3, DUSP1, TNFAIP3, KLF6, PPP1R15A, and EGR1) indicating that HCoV-229E shares pathways with this cytokine but activates additional specific sets of genes (Fig 2A)."
28355270
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"It was shown that TNFAIP3 is induced by TNF and IL-1 and might therefore be involved in the regulation of NFkappaB dependent genes in diverse bacterial infections."
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