IndraLab

Statements

USP8 is phosphorylated on Y717. 5 / 5
1 | 4
sparser
"Here, we report that epidermal growth factor receptor (EGFR) kinase suppresses ciliogenesis by directly phosphorylating the deubiquitinase USP8 on Tyr-717 and Tyr-810 in RPE1 cells."
29472535
sparser
"USP8 phosphorylation on Tyr717 and Tyr810 by EGFR kinase elevates its activity and then activates an inhibitory mechanism of ciliogenesis, i.e., EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase [ xref ]."
32512887
sparser
"In contrast, Kasahara et al. [ xref ] reported that EGFR kinase suppresses ciliogenesis by phosphorylating USP8 on Tyr717 and Tyr810 enhancing the deubiquitinase activity."
31845722
sparser
"In this study, we show that EGFR activation is responsible for this process by directly phosphorylating USP8 on Tyr-717 and Tyr-810."
29472535
hprd
No evidence text available
18669648