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USP4 inhibits innate immune response. 2 / 2

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"The inhibition of USP4 promotes the activation of the innate immune response, resulting in an increase in production of interferon-stimulated genes (ISGs) and expression of MHC-I molecules."

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"USP4 also negatively regulates the TLR signaling-mediated innate immune response by removing the K63-linked ubiquitin chain on TAK1 [ 60 ]."

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IndraLab

Statements

USP4 inhibits innate immune response. 2 / 2

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