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YAP1 binds OTUD1. 4 / 4
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"Moreover, His-YAP protein purified from bacteria could be pulled down by GST-OTUD1, but not by GST, in an in vitro binding assay (Fig.  xref ), suggesting that OTUD1 directly interacts with YAP."
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"This non-proteolytic ubiquitination can be reversed by the binding and interaction between deubiquitinase OTUD1 and YAP1; OTUD1 decreases YAP1 stability, and attenuates the cell proliferation and tumor-growth activity of YAP1 ( xref )."
32390875
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"OTUD1 binds YAP and reverses its K63 ubiquitination."
29891922
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"We further validated the interaction between OTUD1 and YAP in vivo and in vitro."
29891922