IndraLab

Statements

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"USP8 promotes CSCC progression by enhancing tumor invasion capacity."
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"Our findings indicated that the proliferation , invasion , and stemness of LN229 and T98G cells were markedly suppressed by USP8 inhibition ."
36816802
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"In conclusion, we demonstrated that USP8 in cancer tissue is an independent prognostic biomarker of CSCC, and high USP8 in CSCC can enhance cell invasion."
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"Meanwhile, USP8 deficiency could reduce tumor invasion and migration and tumor size in an immunity-dependent manner, and improve anti-tumor immunogenicity."
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"USP8 promotes TGF-β/SMAD-induced epithelial-mesenchymal transition (EMT), invasion, and metastasis in tumor cells."
35811497
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"Our findings indicated that the proliferation, invasion, and stemness of LN229 and T98G cells were markedly suppressed by USP8 inhibition."
36816802
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"Moreover, we conducted cellular studies and found that USP8 can significantly upregulate the migration and invasion processes of CSCC cell lines."
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"However, both the migration and invasion capacities of CSCC cells were upregulated by USP8 overexpression (XREF_FIG)."
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"Knockdown of USP8 inhibited the proliferation, migration, invasion, and cell cycle progression of A549 and H1299 cells, and promoted the apoptosis."
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"Knockdown of USP8 Inhibits the Migration and Invasion of Lung Cancer Cells."
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"In addition, USP8 depletion inhibited the proliferation, invasion and stemness of HCC cells and conferred ferroptosis resistance, which effects could be further rescued by β-catenin overexpression."
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"We demonstrated that knockdown of USP8 significantly inhibited the proliferation, migration and invasion of QBC939 and RBE cells in vitro, while USP8 overexpression showed significant promoting effects on Hucct-1 cells."
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"Cellular studies showed that USP8 can enhance the proliferation, migration, and invasion abilities of CSCC cells, thereby promoting tumor progression."
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