IndraLab

Statements

eidos
"CSN6 induces EMT and enhances metastasis of breast cancer cells by reducing Snail1 ubiquitination ."
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"Together, the results suggest that CSN6 may positively regulate beta-catenin transcription, thereby mediating the EMT."
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"Additionally, CSN6 was found to promote EMT by inhibiting E-cadherin, which were significantly mitigated via upregulation of Snail as a result of MEK and ERK pathway activation."
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"In addition, studies shown that CSN6 has the function of deubiquitinase and promoted tumorigenesis, proliferation, metastasis and EMT by inhibiting substrates degradation [ 14–16 ]."
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"CSN6 promotes PTC progression by inducing the EMT."
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"In HCC, CSN6 overexpression promotes epithelial-mesenchymal transition and predicts poor prognosis (26)."
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