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BAP1 inhibits RNF2. 2 / 2

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"Subsequent RNA-seq experiments revealed that Bap1 knockout in ES cells causes Rnf2-dependent down-regulation of the pro-survival genes Bcl2 and Mcl1."

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reach

"As for the reported tumor suppressive mechanism, BAP1 can antagonize EZH2 and PRC2 or RING1B (RNF2)/PRC1 in a tissue specific manner."

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IndraLab

Statements

BAP1 inhibits RNF2. 2 / 2

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