IndraLab

Statements

USP40 deubiquitinates CFLAR. 3 / 3
| 3
reach
"Results show that overexpression of USP40 decreased the ubiquitination of CFLAR (Fig. 4d), and knockdown USP40 increased the ubiquitination of CFLAR (Fig. 4e)."
31046799
reach
"Studies have shown that USP40 deubiquitinates and stabilizes CFLAR , and GMEB1 interacts with USP40 to maintain CFLAR and prevent apoptosis in NSCLC [11]."
38308285
reach
"In non-small cell lung cancer (NSCLC), USP40 suppresses polyubiquitination of anti-apoptotic protein CFLAR , and GMEB1 promotes CFLAR stability via USP40, followed by inhibition of CASP8 precursor activation and apoptosis [11]."
38308285