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Amodiaquine inhibits RNApo_I. 2 / 2

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"A noteworthy example is the antimalarial drug amodiaquine, which triggers the degradation of the Pol I subunit RPA194, effectively suppressing rDNA transcription in a manner akin to BMH-21 (281)."

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"Amodiaquine triggers degradation of the catalytic subunit of RNA polymerase I (Pol I), with ensuing RPL5 and RPL11 dependent stabilization of p53."

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IndraLab

Statements

Amodiaquine inhibits RNApo_I. 2 / 2

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