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"Furthermore, malignant epithelial cells may accelerate the proliferation of CD4 Tregs and CD8 Tex through CALM1/FAS binding, and then activate the downstream nuclear factor kB (NF‐kB) transcript factors, such as NFKBIA, NFKB2 and REL, regulating downstream CCND2, CDK6 and TRAF1 expression (Figure S5)."