IndraLab

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USP7 activates Proteasome. 1 / 2

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"Mechanistic studies revealed that arsenic plus BaP co-exposure up-regulates MCL-1 protein levels by synergistically activating the PI3K/Akt/mTOR pathway to increase the level of a deubiquitinase USP7, which in turn reduces the level of MCL-1 protein ubiquitination and prevents its subsequent proteasome degradation."

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IndraLab

Statements

USP7 activates Proteasome. 1 / 2

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