IndraLab

Statements

Sotrastaurin inhibits ACE2. 2 / 2

| 1 1

sparser

"In cells maintained in 7.8 mM D -glucose, ACE2 shedding was significantly inhibited by the pan-protein kinase C (PKC) competitive inhibitor sotrastaurin, but not by an inhibitor of ADAM17."

27313531

➶

reach

"On the other hand, sotrastaurin (10 -5 M) completely inhibited ACE2 shedding under conditions of high D-glucose (28 mM), to levels observed under basal conditions, with or without TAPI-1."

27313531

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

Sotrastaurin inhibits ACE2. 2 / 2

INDRA sources:

Databases

Reading