IndraLab

Statements

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"These results suggest that Uch-L3 can deubiquitinate the poly-ubiquitinated Smad1.We then tested whether Uch-L3, a possible DUB enzyme of Smad1, is able to accelerate the differentiation of osteoblast[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Consequently, it was suggested that UCHL3 stabilizes Smad1 signaling, which may explain the enhanced osteoblast differentiation caused by UCHL3 overexpression."
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"UCH-L3 promotes the differentiation of osteoblast from C2C12 cells, while knockdown of Uch-l3 delays osteoblast differentiation [73]."
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"Even though the function of UCH-L3 in neurons has not been elucidated to the extent of our knowledge, it may be plausible that there can be reciprocal or differential functions of UCH-L3 to the UCH-L1[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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