IndraLab

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USP18 inhibits interferon receptor. 3 / 3
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"USP18 inhibits type I interferon signaling by preventing Janus-associated kinase 1 (JAK1) pathway from binding to type I interferon receptor."

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"USP18 inhibits type I interferon signaling by preventing Janus-associated kinase 1 (JAK1) from binding to the type I interferon receptor."

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"In addition to its isopeptidase activity, USP18 negatively regulates type I and type III IFN signalling by blocking the IFNAR2 subunit of the interferon receptor ."