IndraLab

Statements

Homocysteine activates KCNMA1. 3 / 3
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"Taken together, our data show that elevation of cellular Hcy level induces oxidative stress, increases BK channel activity, and decreases exocytosis of secretory granules."
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"We previously demonstrated that TMP may protect coronary artery from homocysteine-induced functional impairment by restoring BK channel activity, and suppression of ER stress-mediated downregulation of the β1 subunit of BK channel is the underlying mechanism [22]."
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"Homocysteine augments BK channel activity and decreases exocytosis of secretory granules in rat GH3 cells."
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