IndraLab

Statements


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reach
"Mechanistically, OTUB2 cleaves K6- and K63-associated ubiquitin linkages on signal transducer and activator of transcription 1 (STAT1), resulting in enhanced phosphorylation at Tyr701, dimerization, a[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

sparser
"The above results indicated that the interaction between OTUB2 and STAT1 is dependent on the enzymatic activity of OTUB2."

reach
"The above results indicated that the interaction between OTUB2 and STAT1 is dependent on the enzymatic activity of OTUB2."

sparser
"We found that OTUB2 specifically interacts with STAT1 and primarily cleaves K6- and K63-linked ubiquitin chains on STAT1."