IndraLab

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FBXL3 inhibits mutated ATXN3. 1 / 1

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"We overexpressed FBXL3 in SCA3 NPCs and confirmed that high levels of FBXL3 reduce endogenous levels of both wild-type and mutant ATXN3 proteins to 58% and 64%, respectively, of control levels (XREF_FIG)."

31783119

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IndraLab

Statements

FBXL3 inhibits mutated ATXN3. 1 / 1

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